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Uridine → 2'-O-Nonyluridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Uridine | HCID 6029 | — |
| 反応物 | 1-Iodononane | HCID 20275 | — |
| 反応物 | Dibutyltin oxide | HCID 61221 | — |
| 反応物 | 2',3'-O-dibutylstannyleneuridine | HCID 131720090 | — |
| 生成物 | 2'-O-Nonyluridine | HCID 22874743 | — |
反応手順
As per the procedure of Example 49, uridine (22.5 g) was treated with dibutyl tin oxide (22.5 g, 1 eq). The resulting 2',3'-O-dibutylstannyleneuridine was treated with iodononane (11 ml, 1.3 eq.) at 130-140° C. as per Example 50 to give the 2' and 3' isomers (11.2 g) as an oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06133438 |
| 出典データセット | uspto-grants-2000_10 |
| ORD ID | ord-70c2c22e48174b57af0222159c25dc72 |
| 出典メモ | uspto-grants-2000_10 |