Acetone → 6-(2-Chlorobenzoyl)-5-(2-nitroethenylamino)indan

HRID 36929ノート

反応式

HRID 36929 の反応式
O1[CH2:6][CH2:5][N:4]([CH:7]=[CH:8][N+:9]([O-:11])=[O:10])CC1.NC1C=[C:15]2[C:19](=[CH:20][C:21]=1[C:22](=[O:30])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[Cl:29])[CH2:18][CH2:17][CH2:16]2.Cl.CC(C)=O>O>[Cl:29][C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=1[C:22]([C:21]1[CH:20]=[C:19]2[C:18]([CH2:17][CH2:16][CH2:15]2)=[CH:6][C:5]=1[NH:4][CH:7]=[CH:8][N+:9]([O-:11])=[O:10])=[O:30]

参加物

6

反応物 4

HCID 180AcetoneHCID 313Hydrochloric AcidHCID 683970Morpholine, 4-(2-nitroethenyl)-HCID 199365705-Amino-6-(2-chlorobenzoyl)indan

生成物 1

HCID 677827716-(2-Chlorobenzoyl)-5-(2-nitroethenylamino)indan収率 95.2%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

1-Morpholino-2-nitroethene (3.93 g) was added to a mixture of 5-amino-6-(2-chlorobenzoyl)indan (4.50 g), 6N HCl (15 ml) and acetone (45 ml) and the whole mixture was stirred at room temperature for one hour. To this reaction mixture was added water to give crystals of 6-(2-chlorobenzoyl)-5-(2-nitroethenylamino)indan (5.40 g, 95.2%). Recrystallization from ethanol gave yellow needles, mp. 225°-226° C.

出典と根拠

ORDレコード
ord-223d5f6f070c4357b70dc067fd0a20e8
出典データセット
uspto-grants-1995_05
特許番号
US05418239

反応ノート

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