Triethylamine → 5-(2-Methylbenzoyloxy)indan
反応式
[OH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH2:7][CH2:6][CH2:5]2.C(N(CC)CC)C.[CH3:18][C:19]1[CH:27]=[CH:26][CH:25]=[CH:24][C:20]=1[C:21](Cl)=[O:22]>ClCCl>[CH3:18][C:19]1[CH:27]=[CH:26][CH:25]=[CH:24][C:20]=1[C:21]([O:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH2:7][CH2:6][CH2:5]2)=[O:22]参加物
5
実験手順
To an ice-cooled mixture of 5-hydroxyindan (13.4 g), triethylamine (14.0 ml) and dichloromethane (150 ml) was added 2-methylbenzoyl chloride (15.4 ml) dropwise with constant stirring. The mixture was further stirred under ice-cooling for one hour, after which it was washed with water and dried (MgSO4). The solvent was then distilled off to give 5-(2-methylbenzoyloxy)indan as oil in quantitative yield.
後処理
- temperaturecooling for one hour
- washafter which it was washed with water
- dry with materialdried (MgSO4)
- distillationThe solvent was then distilled off
出典と根拠
- ORDレコード
- ord-4a2639ed63af4ae696074f62c7fedcef
- 出典データセット
- uspto-grants-1995_05
- 特許番号
- US05418239
反応ノート
読み込み中…