Dimethylformamide dimethyl acetal → Ethyl 2-cyano-5-dimethylamino-3-methylpenta-2,4-dienoate
反応式
[C:1](=[C:4]([C:10]#[N:11])[C:5]([O:7][CH2:8][CH3:9])=[O:6])([CH3:3])[CH3:2].CO[CH:14](OC)[N:15]([CH3:17])[CH3:16]>C(O)C>[C:10]([C:4](=[C:1]([CH3:2])[CH:3]=[CH:14][N:15]([CH3:17])[CH3:16])[C:5]([O:7][CH2:8][CH3:9])=[O:6])#[N:11]参加物
4
実験手順
A mixture of 127.7 g (0.839 mole) of ethyl isopropylidenecyanoacetate (4) and 100 g (0.839 mole) of N.N-dimethylformamide dimethyl acetal in 500 mL of ethanol was refluxed for 24 hours. The ethanol was removed under reduced pressure to give 124 g (100%) of a dark oil.
後処理
- temperaturewas refluxed for 24 hours
- customThe ethanol was removed under reduced pressure
出典と根拠
- ORDレコード
- ord-0e34adf709a642c9b585539b628c6eb3
- 出典データセット
- uspto-grants-2000_10
- 特許番号
- US06136982
反応ノート
読み込み中…