化工社化工社 化学情報印刷レポート · 研究参考用
Phenol → Methyl-4-(trans-2-decenyloxy)-benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenol | HCID 996 | — |
| 反応物 | 2-Decen-1-ol | HCID 87630 | — |
| 反応物 | Methyl 4-(octadecyloxy)benzoate | HCID 4189536 | — |
| 反応物 | Diethyl azodicarboxylate | HCID 5462977 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | Methyl-4-(trans-2-decenyloxy)-benzoate | HCID 18521070 | 65% |
反応手順
Phenol 34 (486 mg, 3.2 mmol), 2-decenol 26 g (500 mg, 3.2 mmol), TPP (965 mg, 3.68 mmol), and DEAD (641 mg, 3.68 mmol) in 32 ml ether were reacted according to the procedure for compound 35a. The crude product was purified via flash chromatography over silica gel with gradual elutions from 95/5-90/10 (v/v, Hex/EtOAc). Evaporation of solvent yielded 603 mg (65%) of colorless needles.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06139771 |
| 出典データセット | uspto-grants-2000_10 |
| ORD ID | ord-18a140bcba8640bf90b50ad97f4e25ab |
| 出典メモ | uspto-grants-2000_10 |