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Phenol → Methyl-4-(trans-3-decenyloxy)-benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenol | HCID 996 | — |
| 反応物 | Methyl 4-(octadecyloxy)benzoate | HCID 4189536 | — |
| 反応物 | 3-Decen-1-ol, (3E)- | HCID 5352493 | — |
| 反応物 | Diethyl azodicarboxylate | HCID 5462977 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | Methyl-4-(trans-3-decenyloxy)-benzoate | HCID 18521096 | 85% |
反応手順
Ester 34 (500 mg, 3.29 mmol), 3-decenol 26h (514 mg, 3.29 mmol), TPP (992 mg, 3.78 mmol), DEAD (658 mg, 3.78 mmol), and 33 ml ether were reacted according to the procedure for compound 35a. The crude product was purified via flash chromatography over silica gel with gradual elutions from 95/5-90/10 (v/v, Hex/EtOAc). Evaporation of solvent yielded 810 mg (85%) of colorless liquid which was not quite pure. The product was used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06139771 |
| 出典データセット | uspto-grants-2000_10 |
| ORD ID | ord-6fce36808b4841f78ea78c017314a9bc |
| 出典メモ | uspto-grants-2000_10 |