化工社化工社 化学情報印刷レポート · 研究参考用
1,2,3,4-Tetrahydroquinoline → 4-(1,2,3,4-Tetrahydroquinolin-1-yl)-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,2,3,4-Tetrahydroquinoline | HCID 69460 | — |
| 反応物 | 4-chloro-5,6-dimethyl-7H-pyrrolo(2,3-d)pyrimidine | HCID 13041144 | — |
| 溶媒 | Toluene acetone | HCID 20247278 | — |
| 生成物 | 4-(1,2,3,4-Tetrahydroquinolin-1-yl)-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine | HCID 23282462 | — |
反応手順
This product is prepared in a manner analogous to that described in Example 1 from 4-chloro-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine and 1,2,3,4-tetrahydroquinoline (4 equivalents, Fluka, Buchs, Switzerland). M.p: 263-264° C.; FAB-MS: (M+H)+ =279 (corresponds to C17H18N4); Rf value (toluene-acetone--(4:6))=0.29.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06140317 |
| 出典データセット | uspto-grants-2000_10 |
| ORD ID | ord-76ac5485e1334e7499be9b28474d231e |
| 出典メモ | uspto-grants-2000_10 |