化工社化工社 化学情報印刷レポート · 研究参考用
1,2,3,4-Tetrahydroquinoline → 4-(1,2,3,4-Tetrahydroquinolin-1-yl)-6-(4-nitro-phenyl)-7H-pyrrolo[2,3-d]-pyrimidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,2,3,4-Tetrahydroquinoline | HCID 69460 | — |
| 反応物 | 4-Chloro-6-(4-nitrophenyl)-7H-pyrrolo[2,3-d]pyrimidine | HCID 21262605 | — |
| 溶媒 | Toluene acetone | HCID 20247278 | — |
| 生成物 | 4-(1,2,3,4-Tetrahydroquinolin-1-yl)-6-(4-nitro-phenyl)-7H-pyrrolo[2,3-d]-pyrimidine | HCID 23282467 | — |
反応手順
This product is prepared in a manner analogous to that described in Example 6 from 4-chloro-6-(4-nitro-phenyl)-7H-pyrrolo[2,3-d]pyrimidine and 1,2,3,4-tetrahydroquinoline (2.1 equivalents). FAB-MS: (M+H)+ =372 (corresponds to C21H17N5O2); Rf value (toluene-acetone--4:6)=0.36.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06140317 |
| 出典データセット | uspto-grants-2000_10 |
| ORD ID | ord-9289d9a114744dd7accf6a10d1f409e5 |
| 出典メモ | uspto-grants-2000_10 |