化工社化工社 化学情報印刷レポート · 研究参考用
Boron trifluoride etherate → 2,3,5,6-Tetrafluorophenyl trifluoroacetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Boron trifluoride etherate | HCID 8000 | — |
| 反応物 | Trifluoroacetic anhydride | HCID 9845 | — |
| 反応物 | 2,3,5,6-Tetrafluorophenol | HCID 69858 | — |
| 生成物 | 2,3,5,6-Tetrafluorophenyl trifluoroacetate | HCID 15334258 | 75% |
反応手順
Trifluoroacetic anhydride (28 mL, 0.2 mol) was added dropwise with stirring to 27.1 g (0,163 mol) of 2,3,5,6tetrafluorophenol. Boron trifluoride etherate (0.2 mL) was added and the mixture was refluxed overnight. The residual solution was distilled at atmospheric pressure to remove trifluoroacetic anhydride and trifluoroacetic acid. The desired product 18 (32.2 g; 75% yield) was collected at 45° C. (18mm) as a colorless liquid:
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05419966 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-0f9b25f93fa74c2990bd28e8b3c03f57 |
| 出典メモ | uspto-grants-1995_05 |