化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 9-(2-Deoxy-2-fluoro-beta-D-ribofuranosyl)adenine hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Isopropanol | HCID 3776 | — |
| 反応物 | 2'-Fluoro-2'-deoxyadenosine | HCID 100253 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 9-(2-Deoxy-2-fluoro-beta-D-ribofuranosyl)adenine hydrochloride | HCID 67740756 | — |
反応手順
To a solution of 9-(2-deoxy-2-fluoro-β-D-ribofuranosyl)adenine (500 mg. 1.86 mmol) in MeOH (40 ml) and water (10 ml) was added a solution of isopropanol (15 ml) previously saturated with HCl gas. The solution was evaporated under vacuum at room temperature, and triturated with EtOH (25 ml) to afford the title compound as a white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05420115 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-6f3bdcf96f5c441380f7fe1672130045 |
| 出典メモ | uspto-grants-1995_05 |