化工社化工社 化学情報印刷レポート · 研究参考用
Glycolic Acid → 4,4'-Methylenebis(hydroxyacetamidocyclohexane)
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Glycolic Acid | HCID 757 | — |
| 反応物 | 4,4'-Diaminodicyclohexylmethane | HCID 15660 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Isopropanol | HCID 3776 | — |
| 生成物 | 4,4'-Methylenebis(hydroxyacetamidocyclohexane) | HCID 54218166 | — |
反応手順
4,4'-Methylenebis(cyclohexylamine) (56.5 g, 0.27 mole) was dissolved in hot isopropanol (500 ml) and glycolic acid (40.9 g, 0.54 mole) added portion-wise with stirring. Upon cooling, a white gummy solid separated which was isolated by decantation and redissolved in a small volume of ethanol. Crystallization produced a white crystalline, deliquescent solid; m.p. 96°-102° C. Thorough drying under vacuum increased the melting point (m.p. 149°-151° C.) and reduced the deliquescence.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04529792 |
| 出典データセット | uspto-grants-1985_07 |
| ORD ID | ord-c58731c0f88949cf8bb000b49c348c0d |
| 出典メモ | uspto-grants-1985_07 |