化工社化工社 化学情報印刷レポート · 研究参考用
Glycolic Acid → 4,4'-Methylenebis(hydroxyacetamidocyclohexane)
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Glycolic Acid | HCID 757 | — |
| 反応物 | 4,4'-Diaminodicyclohexylmethane | HCID 15660 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 4,4'-Methylenebis(hydroxyacetamidocyclohexane) | HCID 54218166 | 87% |
反応手順
4,4'-Methylenebis(cyclohexylamine) (25 g, 0.12 mole) and glycolic acid (18.2 g, 0.24 mole) were combined in a 250 ml round bottom flask heated in an oil bath. The solids were melted together with mixing and heated to 175° C. whereupon distillation of water occurred. After heating for 3 hours the evolution of water subsided and crystallization commenced. The solid was removed and recrystallized from methanol to yield 34 g (87%) of lustrous white needles; m.p. 208°-212° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04529792 |
| 出典データセット | uspto-grants-1985_07 |
| ORD ID | ord-2bd0f103b0b04ca6a0b7d61ad900734e |
| 出典メモ | uspto-grants-1985_07 |