Methanol → Methyl 4-phenylthiobenzoate

HRID 37149

反応式

HRID 37149 の反応式
[C:1]1([C:7]2[CH:15]=[CH:14][C:10]([C:11]([OH:13])=[S:12])=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(=O)(=O)(O)O.[CH3:21]O>>[C:1]1([C:7]2[CH:8]=[CH:9][C:10]([C:11]([O:13][CH3:21])=[S:12])=[CH:14][CH:15]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 178526127HCID 178526127、化合物

生成物 1

HCID 54459547Methyl 4-phenylthiobenzoate

実験手順

A mixture of 26.29 g of 4-phenylthiobenzoic acid, 5 ml of concentrates sulfuric acid, and 400 ml of methanol was refluxed for 10 hours while stirring. After reaction, the reaction mixture was concentrated in vacuo, and 400 ml of ethyl acetate was added to the residue, and the mixture was washed with saturated brine (200 ml×3), and dried in anhydrous magnesium sulfate, concentrated in vacuo, and methyl 4phenylthiobenzoate was obtained (27.44 g).

後処理

  1. temperaturewas refluxed for 10 hours
  2. customAfter reaction
  3. concentrationthe reaction mixture was concentrated in vacuo, and 400 ml of ethyl acetate
  4. additionwas added to the residue
  5. washthe mixture was washed with saturated brine (200 ml×3)
  6. dry with materialdried in anhydrous magnesium sulfate
  7. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-533ad2a3f35548f58abae14dec4e6bd0
出典データセット
uspto-grants-1995_05
特許番号
US05420128

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