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Trifluoroacetyl chloride → 1-hydroxy-5,6-dichloro-2-trifluoromethyl-1H-imidazo(4,5-b)-pyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trifluoroacetyl chloride | HCID 61106 | — |
| 反応物 | 5,6-Dichloro-3-nitropyridin-2-amine | HCID 15392047 | — |
| 反応物 | 5,6-Dichloro-2-trifluoroacetamido-3-nitropyridine | HCID 20355477 | — |
| 生成物 | 1-hydroxy-5,6-dichloro-2-trifluoromethyl-1H-imidazo(4,5-b)-pyridine | HCID 20355499 | — |
反応手順
In like procedures, 5,6-dichloro-2-amino-3-nitropyridine was reacted with trifluoroacetyl chloride and the resulting 5,6-dichloro-2-trifluoroacetamido-3-nitropyridine was hydrogenated to obtain 1-hydroxy-5,6-dichloro-2-trifluoromethyl-1H-imidazo(4,5-b)-pyridine, m.p. 207°-208° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04087432 |
| 出典データセット | uspto-grants-1978_05 |
| ORD ID | ord-a0c16f6717aa49e3969304dbb3913955 |
| 出典メモ | uspto-grants-1978_05 |