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Trimetazidine → 7-Hydroxy-2-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylcarbonyl]-2,3-dihydro-1,4-benzodioxin
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trimetazidine | HCID 21109 | — |
| 反応物 | 7-Hydroxy-2,3-dihydro-1,4-benzodioxine-2-carboxylic acid | HCID 10899551 | — |
| 生成物 | 7-Hydroxy-2-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylcarbonyl]-2,3-dihydro-1,4-benzodioxin | HCID 11102312 | 65% |
反応手順
That compound is obtained in a yield of 65% starting from 1-(2,3,4-trimethoxy benzyl)piperazine and 7-hydroxy-2,3-dihydro-1,4-benzodioxin-2-carboxylic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05420132 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-e2d3a32352c3451a856d603947c115da |
| 出典メモ | uspto-grants-1995_05 |