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O-Cresol → 1-Methyl[cyclohexyl]-3-cyclohexyl[methyl]-5-(methoxy-carbonyl-methylene)-hydantoin
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | O-Cresol | HCID 335 | — |
| 反応物 | 1-Cyclohexyl-3-methylurea | HCID 308344 | — |
| 反応物 | 1-Cyclohexyl-3-methylimidazolidine-2,4-dione | HCID 1521461 | — |
| 反応物 | Dimethyl maleate | HCID 5271565 | — |
| 反応物 | 3-Cyclohexyl-1-methylimidazolidine-2,4-dione | HCID 16093102 | — |
| 生成物 | 1-Methyl[cyclohexyl]-3-cyclohexyl[methyl]-5-(methoxy-carbonyl-methylene)-hydantoin | HCID 70627789 | — |
反応手順
78 g of N-methyl-N'-cyclohexyl urea, 220 g of cresol and 72 g of dimethyl maleate were stirred at 185° C for one hour and then at 200° C for one hour. 15 g of methanol distilled over during this time. After fractional distillation, a main fraction boiling at 180°-185° C/0.08 Torr could be isolated. It consisted of an isomeric mixture of 1-methyl-3-cyclohexyl-hydantoin and 1-cyclohexyl-3-methylhydantoin but its exact composition could not be determined by gas chromatography.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04089860 |
| 出典データセット | uspto-grants-1978_05 |
| ORD ID | ord-71f239a28a5e4e13ac7d6c3ae3967c0a |
| 出典メモ | uspto-grants-1978_05 |