Moroxydine hydrochloride → Moroxydine
反応式
[CH2:1]1[N:6]([C:7]([N:9]=[C:10]([NH2:12])[NH2:11])=[NH:8])[CH2:5][CH2:4][O:3][CH2:2]1.Cl.[C:14]([OH:21])(=[O:20])/[CH:15]=[CH:16]\[C:17]([OH:19])=[O:18]>O>[CH2:5]1[N:6](/[C:7](/[NH2:8])=[N:9]/[C:10]([NH2:12])=[NH:11])[CH2:1][CH2:2][O:3][CH2:4]1.[CH2:5]1[N:6](/[C:7](/[NH2:8])=[N:9]/[C:10]([NH2:12])=[NH:11])[CH2:1][CH2:2][O:3][CH2:4]1.[C:14]([O-:21])(=[O:20])/[CH:15]=[CH:16]\[C:17]([O-:19])=[O:18]参加物
5
実験手順
Alternatively, the free base of moroxydine is prepared, e.g.: 2.1 g. moroxydine hydrochloride is dissolved in 100 ml. water and treated with an anion exchange resin. The resulting solution is neutralized, for example, with maleic acid and evaporated to crystallization yielding moroxydine maleate.