化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Hydroxide → Phenoxathiin
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Sodium Azide | HCID 33557 | — |
| 反応物 | 2-Cyanophenoxathiin | HCID 20384188 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | Phenoxathiin | HCID 9217 | — |
反応手順
2-cyanophenoxathiin (2.25g), sodium azide (0.68g) ammonium chloride (0.59g) and dimethylformamide (30 ml.) were heated for 9 hours at 130° C. The solution was poured onto ice and 2 Normal sodium hydroxide solution, and extracted with chloroform. The aqueous phase was acidified with concentrated hydrochloric acid. The solid was filtered, washed and dried to give 2-5-tetrazolyl)phenoxathiin m.p. 210°-2° C. Recrystallisation from glacial acetic acid raised the melting point to 220°-1° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04091108 |
| 出典データセット | uspto-grants-1978_05 |
| ORD ID | ord-e1744285232049b1864671742705fa89 |
| 出典メモ | uspto-grants-1978_05 |