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5-Bromo-2-hydroxypyridine → 5-(Phenylthio)-2-pyridone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Bromo-2-hydroxypyridine | HCID 599528 | — |
| 反応物 | benzenethiol, potassium salt | HCID 11789364 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 生成物 | 5-(Phenylthio)-2-pyridone | HCID 20326562 | — |
反応手順
A solution of 5-bromo-2-pyridone (17.3 g 0.1 mole) in N-methylpyrrolidinone (250 ml.) and potassium thiophenoxide (18.1 g, 0.12 mole) is heated at reflux for 12 hours under a nitrogen atmosphere. The reaction mixture is cooled and diluted with water. The product is collected by filtration, washed with water and dried to yeild 5-(phenylthio)-2-pyridone.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04092321 |
| 出典データセット | uspto-grants-1978_05 |
| ORD ID | ord-9ca0a3824ae444c9b4fee4d9894b9db9 |
| 出典メモ | uspto-grants-1978_05 |