HCID 53691605、化合物 → HCID 54393979、化合物

反応式

ClC1C(OC(=O)[C@H:10]([CH2:19][C:20]2[CH:25]=[CH:24][C:23]([C:26]([CH3:29])([CH3:28])[CH3:27])=[CH:22][CH:21]=2)[NH:11][C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13])=C(Cl)C(Cl)=C(Cl)C=1Cl.[CH2:35]([O:42][C:43](=[O:71])[C@H:44]([CH2:67][CH2:68][S:69][CH3:70])[NH:45][C:46](=[O:66])[C@H](CC1C2C(=CC=CC=2)NC=1)NC(OC(C)(C)C)=O)[C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1>>[CH2:35]([O:42][C:43](=[O:71])[C@H:44]([CH2:67][CH2:68][S:69][CH3:70])[NH:45][C:46](=[O:66])[C@H:10]([CH2:19][C:20]1[CH:21]=[CH:22][C:23]([C:26]([CH3:29])([CH3:28])[CH3:27])=[CH:24][CH:25]=1)[NH:11][C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13])[C:36]1[CH:37]=[CH:38][CH:39]=[CH:40][CH:41]=1

参加物

反応物 2

HCID 53691605HCID 53691605、化合物

HCID 53790063HCID 53790063、化合物

生成物 1

HCID 54393979HCID 54393979、化合物

実験手順

When an equivalent quantity of N-t-butoxycarbonyl-p-t-butyl-L-phenylalanine pentachlorophenyl ester is substituted for the N-t-butoxycarbonyl-L-tryptophan 2,4,5-trichlorophenyl ester of Example 5 and the procedure detailed therein substantially repeated, there is obtained N-t-butoxycarbonyl-p-t-butyl-L-phenylalanyl-L-methionine benzyl ester.

出典と根拠

ORDレコード: ord-2157a97b03e941788bd6d85e7973ca3f
出典データセット: uspto-grants-1978_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04092304

反応ノート

読み込み中…