Phosphonoacetic Acid → Methylacetylphosphonate

HRID 372824ノート

反応式

HRID 372824 の反応式
[P:1]([CH2:5][C:6]([OH:8])=[O:7])([OH:4])([OH:3])=[O:2].[CH3:9]O>>[P:1]([CH2:5][C:6]([O:8][CH3:9])=[O:7])([OH:4])([OH:3])=[O:2]

参加物

3

反応物 2

HCID 546Phosphonoacetic AcidHCID 887Methanol

生成物 1

HCID 170449Methylacetylphosphonate

実験手順

Phosphonoacetic acid, 5 g., was dissolved in 25 ml. methyl alcohol. Dry hydrogen chloride was bubbled through the solution for 30 minutes at O° C. The solution was refluxed for 4 hours. Evaporation of the solvent left an oil which was dried in vacuo over P2O5 and NaOH.

後処理

  1. dissolution, was dissolved in 25 ml
  2. customDry hydrogen chloride was bubbled through the solution for 30 minutes at O° C
  3. temperatureThe solution was refluxed for 4 hours
  4. customEvaporation of the solvent
  5. waitleft an oil which
  6. dry with materialwas dried in vacuo over P2O5 and NaOH

出典と根拠

ORDレコード
ord-e713fe8e17ed41778c36d3a33e7ed9e7
出典データセット
uspto-grants-1978_05
特許番号
US04092412

反応ノート

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