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HRID 372862作成日:2026年10月26日

DL-norvaline → Tylosin

https://huagongshe.com/reaction/372862

反応式

関与物質

役割名称HCID仕込み量
反応物DL-norvalineHCID 824—
反応物L-LeucineHCID 6106—
反応物TylvalosinHCID 6441094—
生成物TylosinHCID 5280440—

反応手順

The conversion reaction was carried out in a manner similar to Example 4 with the same strain, in which L-leucine was used in substitution for DL-norvaline in Example 4 as the isovaleryl donor. About 400 mg of white crystals of 3-acetyl-4"-isovaleryltylosin were obtained from 3 g of tylosin.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04092473
出典データセットuspto-grants-1978_05
ORD IDord-b9dba08818614ad680075d005b94535b
出典メモuspto-grants-1978_05