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Benzyl Chloride → N,N-Dimethyl-N-(2-benzoylaminoethyl)benzylammonium Chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl Chloride | HCID 7503 | — |
| 反応物 | N-(2-(Dimethylamino)ethyl)benzamide | HCID 113158 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | N,N-Dimethyl-N-(2-benzoylaminoethyl)benzylammonium Chloride | HCID 19811098 | — |
反応手順
A solution of 19.23 grams (0.10 mol) of the N-(2-dimethylaminoethyl)benzamide, prepared as described in Example 1, 12.66 grams (0.10 mol) of α-chlorotoluene and 64 milliters of acetonitrile was heated at reflux for 19.75 hours. Solid crystallized on cooling which was collected, washed with acetonitrile and dried. The yield of product was 24.0 grams (75.27% of theory); mp=175°-176° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05162188 |
| 出典データセット | uspto-grants-1992_11 |
| ORD ID | ord-80630acfb6e64d19be126317e4c1d130 |
| 出典メモ | uspto-grants-1992_11 |