1,3-Dimethyl-5-ethoxycarbonylbarbituric acid → HCID 19811558、化合物

HRID 373105ノート

反応式

HRID 373105 の反応式
[F:1][C:2]([F:23])([O:9][CH:10]([F:22])[C:11]([F:21])([F:20])[O:12][C:13]1[CH:19]=[CH:18][C:16]([NH2:17])=[CH:15][CH:14]=1)[C:3]([F:8])([F:7])[CH:4]([F:6])[F:5].[CH3:24][N:25]1[C:32](=[O:33])[CH:31]([C:34](OCC)=[O:35])[C:29](=[O:30])[N:28]([CH3:39])[C:26]1=[O:27]>C1(C)C=CC=CC=1>[CH3:39][N:28]1[C:29](=[O:30])[CH:31]([C:34](=[O:35])[NH:17][C:16]2[CH:18]=[CH:19][C:13]([O:12][C:11]([F:21])([F:20])[CH:10]([O:9][C:2]([F:23])([F:1])[C:3]([F:7])([F:8])[CH:4]([F:5])[F:6])[F:22])=[CH:14][CH:15]=2)[C:32](=[O:33])[N:25]([CH3:24])[C:26]1=[O:27]

参加物

4

反応物 2

HCID 5937141,3-Dimethyl-5-ethoxycarbonylbarbituric acidHCID 14819451HCID 14819451、化合物

生成物 1

HCID 19811558HCID 19811558、化合物

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

14.50 g (40.6 mmol) of 4-(2-(1,1,2,2,3,3-hexafluoropropoxy)-1,1,2-trifluoroethoxy)-aniline were added to 9.26 g (40.6 mmol) of 1,3-dimethyl-5-ethoxycarbonylbarbituric acid in 100 ml of toluene, the mixture was stired under reflux for 2.5 hours and concentrated and the residue was recrystallized from methanol.

後処理

  1. temperatureunder reflux for 2.5 hours
  2. concentrationconcentrated
  3. customthe residue was recrystallized from methanol

出典と根拠

ORDレコード
ord-df7e9aa50fd54996b8f60d7cfc04b264
出典データセット
uspto-grants-1992_11
特許番号
US05162327

反応ノート

読み込み中…