Dimethylformamide → HCID 19811955、化合物

HRID 373144ノート

反応式

HRID 373144 の反応式
[SH:1][C:2]1[O:3][C:4]([C:7]2[O:11][C:10]([N:12]([CH3:14])[CH3:13])=[N:9][N:8]=2)=[N:5][N:6]=1.O1CCOCC1.CN(C)C=O.Br[CH2:27][CH2:28][C:29]([F:33])=[C:30]([F:32])[F:31]>O>[F:33][C:29](=[C:30]([F:32])[F:31])[CH2:28][CH2:27][S:1][C:2]1[O:3][C:4]([C:7]2[O:11][C:10]([N:12]([CH3:14])[CH3:13])=[N:9][N:8]=2)=[N:5][N:6]=1

参加物

6

反応物 4

HCID 6228DimethylformamideHCID 312751,4-DioxaneHCID 663334-Bromo-1,1,2-trifluorobut-1-eneHCID 178483107HCID 178483107、化合物

生成物 1

HCID 19811955HCID 19811955、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

4.26 g of 2-mercapto-5-(2-dimethylamino-1,3,4-oxadiazol-5-yl)-1,3,4-oxadiazole according to Example H2 are initially introduced into 40 ml of dioxane and stirred with 2.24 g of potassium t-butylate. 4 ml of dimethylformamide and then 4.2 g of 4-bromo-1,1,2-trifluorobut-1-ene are added and the mixture is stirred overnight at room temperature. The mixture is poured into water and the crystals are filtered off with suction. After drying and stirring with ether, 4.6 g of the title compound of melting point 87°-90° C. are obtained.

後処理

  1. filtrationthe crystals are filtered off with suction
  2. customAfter drying
  3. stirringstirring with ether, 4.6 g of the title compound of melting point 87°-90° C.
  4. customare obtained

出典と根拠

ORDレコード
ord-cb0458332f62444597fd8cc0e25ef86f
出典データセット
uspto-grants-1992_11
特許番号
US05162349

反応ノート

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