Ethanol → 1-(4-Methoxyethoxymethoxyphenyl)-2-hydroxy-1-propanone

HRID 373462ノート

反応式

HRID 373462 の反応式
CC1C=CC(S([O-])(=O)=[O:9])=CC=1.[CH:12]1[CH:17]=C[NH+]=CC=1.[CH2:18]([OH:20])C.C(C1C=CC(C2C=CC(C([O:42][CH:43]([CH3:56])[C:44]([C:46]3[CH:51]=[CH:50][C:49]([O:52][CH2:53]C=C)=[CH:48][CH:47]=3)=[O:45])=O)=CC=2)=CC=1)CCCCCC>O>[CH3:18][O:20][CH2:17][CH2:12][O:9][CH2:53][O:52][C:49]1[CH:48]=[CH:47][C:46]([C:44](=[O:45])[CH:43]([OH:42])[CH3:56])=[CH:51][CH:50]=1

参加物

5

反応物 3

HCID 702EthanolHCID 466102Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1)HCID 198100571-Methyl-2-(4'-allyloxy-phenyl)-2-keto-ethyl 4'-heptylbiphenyl-4-ylcarboxylate

生成物 1

HCID 572635601-(4-Methoxyethoxymethoxyphenyl)-2-hydroxy-1-propanone

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

To this compound, 0.5 g of PPTS and 100 ml of ethanol were added, and the resulting mixture was stirred at room temperature. After addition of water, the mixture was extracted with toluene. The organic layer thus obtained was neutralized, washed with water, dried, and then concentrated to obtain the desired (S) 1-(4-methoxyethoxymethoxyphenyl)-2-hydroxy-1-propane.

後処理

  1. extractionthe mixture was extracted with toluene
  2. customThe organic layer thus obtained
  3. washwashed with water
  4. customdried
  5. concentrationconcentrated
  6. customto obtain the

出典と根拠

ORDレコード
ord-1573c6f6679b442a8460970fa997c9e7
出典データセット
uspto-grants-1992_11
特許番号
US05164112

反応ノート

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