4-(4-Octyloxyphenyl)benzoyl chloride → 4-(2-Pentanoyloxy-1-keto-propyl)-phenyl 4'-octyloxybiphenyl-4-ylcarboxylate

HRID 373463ノート

反応式

HRID 373463 の反応式
[CH2:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([C:22](Cl)=[O:23])=[CH:18][CH:17]=2)=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].C(C1C=CC(C2C=CC(C(OC(C)C(C3C=CC(OCC=C)=CC=3)=O)=O)=CC=2)=CC=1)CCCCCC.[C:61]([O:67][CH:68]([CH3:78])[C:69]([C:71]1[CH:76]=[CH:75][C:74]([OH:77])=[CH:73][CH:72]=1)=[O:70])(=[O:66])[CH2:62][CH2:63][CH2:64][CH3:65]>CN(C1C=CN=CC=1)C>[CH2:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([C:22]([O:77][C:74]3[CH:75]=[CH:76][C:71]([C:69](=[O:70])[CH:68]([O:67][C:61](=[O:66])[CH2:62][CH2:63][CH2:64][CH3:65])[CH3:78])=[CH:72][CH:73]=3)=[O:23])=[CH:18][CH:17]=2)=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

参加物

5

反応物 3

HCID 110784734-(4-Octyloxyphenyl)benzoyl chlorideHCID 198100571-Methyl-2-(4'-allyloxy-phenyl)-2-keto-ethyl 4'-heptylbiphenyl-4-ylcarboxylateHCID 198101294-(2-Pentanoyloxy-1-keto-propyl)phenol

生成物 1

HCID 198100404-(2-Pentanoyloxy-1-keto-propyl)-phenyl 4'-octyloxybiphenyl-4-ylcarboxylate

試薬・触媒・溶媒 1

HCID 142844-(Dimethylamino)pyridine触媒

実験手順

A mixture of 500 mg of 4'-octyloxy-biphenyl-4-yl-carboxylic acid chloride, 400 mg of (S) 4-(2-pentanoyloxy-1-keto-propyl)phenol, 600 mg of N,N-dicyclohexylcarbodiimide, and 20 mg of DMAP was stirred at room temperature for three hours. A solid material precipitated was removed by filtration. The organic layer thus obtained was washed with an acid, an alkali, and with water, dried, and then concentrated.

後処理

  1. customA solid material precipitated
  2. customwas removed by filtration
  3. customThe organic layer thus obtained
  4. washwas washed with an acid
  5. dry with materialan alkali, and with water, dried
  6. concentrationconcentrated

出典と根拠

ORDレコード
ord-af6d64d2a7ba4b25a4acd3588fc4cde5
出典データセット
uspto-grants-1992_11
特許番号
US05164112

反応ノート

読み込み中…