化工社化工社 化学情報印刷レポート · 研究参考用
Aminoethyl Nitrate → (2S, 4S)-N-(2-Nitroxyethyl)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Aminoethyl Nitrate | HCID 26001 | — |
| 反応物 | (2S,4S)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carbonyl chloride | HCID 57210646 | — |
| 生成物 | (2S, 4S)-N-(2-Nitroxyethyl)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide | HCID 67944386 | 82.3% |
反応手順
The procedure similar to that as described in Example 8 was carried out with use of 2-nitroxyethylamine and (2S,4S)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carbonyl chloride (Reference Example 1) to give the desired compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05164391 |
| 出典データセット | uspto-grants-1992_11 |
| ORD ID | ord-7f29ef2f5ca4452490e5e7a87a023dc7 |
| 出典メモ | uspto-grants-1992_11 |