6-Methylamino-9-((2R,3R,4S)-3,4-bis(hydroxymethyl)-oxetan-2-yl)purine → 6-Methylamino-9-((2R,3R,4S)-4-hydroxymethyl-3-methyl-oxetan-2-yl)purine

反応式

[CH3:1][NH:2][C:3]1[N:11]=[CH:10][N:9]=[C:8]2[C:4]=1[N:5]=[CH:6][N:7]2[C@H:12]1[C@H:15]([CH2:16]O)[C@@H:14]([CH2:18][OH:19])[O:13]1.OC[C@H]1O[C@@H](N2C=NC3C2=NC=NC=3N)[C@@H]1C>>[CH3:1][NH:2][C:3]1[N:11]=[CH:10][N:9]=[C:8]2[C:4]=1[N:5]=[CH:6][N:7]2[C@H:12]1[C@H:15]([CH3:16])[C@@H:14]([CH2:18][OH:19])[O:13]1

参加物

反応物 2

HCID 677173796-Methylamino-9-((2R,3R,4S)-3,4-bis(hydroxymethyl)-oxetan-2-yl)purine

HCID 677177159-((2R,3R,4S)-4-Hydroxymethyl-3-methyl-oxetan-2-yl) adenine

生成物 1

HCID 677173886-Methylamino-9-((2R,3R,4S)-4-hydroxymethyl-3-methyl-oxetan-2-yl)purine

実験手順

The procedure of Example 9 can be repeated replacing the starting compound of Example 9 (a) with the product of Example 1 to obtain the desired compound.

出典と根拠

ORDレコード: ord-eb63652c357e4cc4a8c833b8d6804712
出典データセット: uspto-grants-1995_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05420276

反応ノート

読み込み中…