Hydrochloric Acid → m-Bromophenyl 3-methyl-2-butenyl sulfide

HRID 37404

反応式

HRID 37404 の反応式
[Br:1][C:2]1[CH:3]=[C:4]([SH:8])[CH:5]=[CH:6][CH:7]=1.C(=O)([O-])[O-].[K+].[K+].[CH3:15][C:16]([CH3:20])=[CH:17][CH2:18]Br.Cl>CN(C)C=O.O>[CH3:15][C:16]([CH3:20])=[CH:17][CH2:18][S:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([Br:1])[CH:3]=1

参加物

7

反応物 4

HCID 313Hydrochloric AcidHCID 11430Potassium CarbonateHCID 700922-Butene, 1-bromo-3-methyl-HCID 80597m-Bromobenzenethiol

生成物 1

HCID 22640690m-Bromophenyl 3-methyl-2-butenyl sulfide収率 98%

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 6228Dimethylformamide溶媒

実験手順

36 g of 3-bromothiophenol were dissolved in 400 ml of dimethylformamide. After the addition of 27 g of finely powdered potassium carbonate and 29 g of 3,3-dimethylallyl bromide, the mixture was stirred at room temperature for 1 hour, diluted with 500 ml of water, acidified with 3N hydrochloric acid while cooling and extracted with ether. The yellow-brown oil obtained after evaporation was distilled in a high vacuum. There were obtained 48 g of m-bromophenyl 3-methyl-2-butenyl sulfide as a colorless liquid, boiling point 85° C./13.3 Pa.

後処理

  1. temperaturewhile cooling
  2. extractionextracted with ether
  3. customThe yellow-brown oil obtained
  4. customafter evaporation
  5. distillationwas distilled in a high vacuum

出典と根拠

ORDレコード
ord-6a109ae7194e4a79adaf25d9e834a073
出典データセット
uspto-grants-1995_05
特許番号
US05420273

関連ノート

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