関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dimethylhydantoin | HCID 6491 | — |
| 反応物 | Diphenyl Ether | HCID 7583 | — |
| 反応物 | 5-Chloro-2-nitrobenzotrifluoride | HCID 67052 | — |
| 生成物 | Nilutamide | HCID 4493 | — |
反応手順
The following were introduced into 288 ml of phenyl oxide: 96.10 grams of 5,5-dimethyl-hydantoin, 170.86 grams of 2-nitro-5-chloro trifluoromethylbenzene and 89.40 grams of cupric oxide. The mixture was heated to 190° C. for about 23 hours, then cooled to 20° C. and filtered. The residue was characterized in the phenyl oxide filtrate by thin layer chromatography.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05166358 |
|---|
| 出典データセット | uspto-grants-1992_11 |
|---|
| ORD ID | ord-250000bbc78844a9a114c6ed9b1ccd4b |
|---|
| 出典メモ | uspto-grants-1992_11 |
|---|
