化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 3-Bromopyridine-4-carbonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 3-Bromoisonicotinic acid | HCID 817972 | — |
| 生成物 | 3-Bromopyridine-4-carbonyl chloride | HCID 13597868 | — |
反応手順
3-Bromopyridine-4-carboxylic acid (5.0 g) was dissolved in thionyl chloride (50 ml) and the solution heated under reflux for 4 hours, cooled and evaporated in vacuo. Re-evaporation of added toluene gave 3-bromopyridine4-carbonyl chloride, m.p.151°-154° C. (dec.) (5.45 g) as a green solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05480857 |
| 出典データセット | uspto-grants-1996_01 |
| ORD ID | ord-f8192f4fac954ba7bd348f63b541c8bf |
| 出典メモ | uspto-grants-1996_01 |