関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 反応物 | 1,4-Benzenedicarboxylic acid, methyl ester | HCID 3614454 | — |
| 触媒 | Dimethylformamide | HCID 6228 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | Monomethyl terephthalate chloride | HCID 22493623 | 82% |
反応手順
To a stirred solution of mono-methyl terephthalate (1 equivalent), toluene (30 ml/gm of ester) and 3 drops of DMF was added dropwise oxalyl chloride (2.0 equivalents). The reaction mixture was stirred at 45° C. for 16 hours. The solution was concentrated under reduced pressure to give the desired product as a pale yellow solid. The product was used without further purification; yield 82.0%; m.p. 50°-52° C. IR (thin film); 2970, 1775, 1720, 1430, 1400, 1280, 1105, 880 cm-1.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05420285 |
|---|
| 出典データセット | uspto-grants-1995_05 |
|---|
| ORD ID | ord-a280955a158d4e889882a189335a59c5 |
|---|
| 出典メモ | uspto-grants-1995_05 |
|---|
