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HRID 374684作成日:2026年10月25日

Trifluoroacetic acid → Caprine

https://huagongshe.com/reaction/374684

反応式

関与物質

役割名称HCID仕込み量
反応物Trifluoroacetic acidHCID 6422—
反応物tert-butyl (2S)-2-aminohexanoateHCID 12451446—
溶媒DichloromethaneHCID 6344—
生成物CaprineHCID 21236—

反応手順

23.5 mg of L-N-[(2R or S)-5-ethylthio-2-(1-naphthylmethyl)pentanoyl]norleucine tert-butyl ester was dissolved in 0.2 ml of dichloromethane, and 0.1 ml of trifluoro acetic acid was added thereto. The mixture was stirred at room temperature for four hours. Then, the reaction solution was concentrated under reduced pressure to obtain 20.7 mg of L-N-[(2R or S)-5-ethylthio-2-(1-naphthylmethyl)pentanoyl]norleucine as colorless solid.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05481036
出典データセットuspto-grants-1996_01
ORD IDord-aa312e5f1bd544c6952f2a6f19a3f20f
出典メモuspto-grants-1996_01