Water → 5-Bromo-6-hydroxy-2-naphthaldehyde

HRID 374869

反応式

HRID 374869 の反応式
[Br:1]Br.[OH:3][C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[CH:10]=[C:9]([CH:14]=[O:15])[CH:8]=[CH:7]2.O>C(O)(=O)C>[Br:1][C:5]1[C:4]([OH:3])=[CH:13][CH:12]=[C:11]2[C:6]=1[CH:7]=[CH:8][C:9]([CH:14]=[O:15])=[CH:10]2

参加物

5

反応物 3

HCID 962WaterHCID 24408BromineHCID 27641106-Hydroxy-2-naphthaldehyde

生成物 1

HCID 189963195-Bromo-6-hydroxy-2-naphthaldehyde収率 94%

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

Step b) Bromine (7.45 mL, 145.3 mmol) was added dropwise to a cold (0° C.) solution of 6-hydroxy-2-naphthaldehyde (25.0 g, 145.3 mmol) in acetic acid (300 mL). After stirring for 30 minutes the mixture was poured into water (21), and the precipitated solid filtered and dried to yield a brown solid (34.5 g, 94% yield, m.p. 189-190).

後処理

  1. filtrationthe precipitated solid filtered
  2. customdried
  3. customto yield a brown solid (34.5 g, 94% yield, m.p. 189-190)

出典と根拠

ORDレコード
ord-e3c8938ecf0449b9b05442428f6fd33f
出典データセット
uspto-grants-1996_01
特許番号
US05482968

関連ノート

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