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Ethylamine → N-Ethyl-2-(4-nitro-1H-imidazol-1-yl)octanoamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethylamine | HCID 6341 | — |
| 反応物 | Ethyl 2-(4-nitro-1H-imidazole-1-yl)octanoate | HCID 10062368 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | N-Ethyl-2-(4-nitro-1H-imidazol-1-yl)octanoamide | HCID 15222339 | — |
反応手順
Ethyl 2-(4-nitro-1H-imidazol-1-yl)octanoate (17 moles, 5.0 g) and ethylamine (20 ml) were stirred in 150 ml ethanol at room temperature for 16 hours. The reaction was added to ice water, extracted with ethyl acetate, washed with water, dried over sodium sulfate and concentrated. The oil crystallized upon standing to yield 3.9 g of N-Ethyl-2-(4-nitro-1H-imidazol-1-yl)octanoamide. (MS).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05484780 |
| 出典データセット | uspto-grants-1996_01 |
| ORD ID | ord-fd4c582d41ef494f8ba2e0064e6fd39f |
| 出典メモ | uspto-grants-1996_01 |