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Chlorine → 1-Chloro-2-(difluoromethoxy)benzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Chlorine | HCID 24526 | — |
| 反応物 | (Difluoromethoxy)benzene | HCID 68015 | — |
| 触媒 | Potassium Chloride | HCID 4873 | — |
| 溶媒 | Benzene, 1,3-bis(trifluoromethyl)- | HCID 223106 | — |
| 生成物 | 1-Chloro-2-(difluoromethoxy)benzene | HCID 13405097 | — |
反応手順
0.5 g of potassium chloride and 10 g of difluoromethoxybenzene in 100 ml of 1,3-bistrifluoromethylbenzene were introduced as the initial charge, and chlorine was then introduced at 100° C. with UV irradiation. In the course of an hour, another 20 g of difluoromethoxybenzene were metered in. After chlorine uptake was complete, the reaction mixture was purged with nitrogen and subsequently distilled. 35.5 g of chlorodifluoromethoxybenzene were isolated (boiling point 144° C., refractive index nD20 1.4479).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05484932 |
| 出典データセット | uspto-grants-1996_01 |
| ORD ID | ord-ce9e40feb79b4bcab347a1604d5df2cc |
| 出典メモ | uspto-grants-1996_01 |