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5,6-Diamino-1,3-diethyluracil → 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(2,5-dimethyl-4-methoxy)phenyl)ethenyl)-, (E)-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5,6-Diamino-1,3-diethyluracil | HCID 4572133 | — |
| 反応物 | 4-Methoxy-2,5-dimethylcinnamic acid | HCID 5199898 | — |
| 生成物 | 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(2,5-dimethyl-4-methoxy)phenyl)ethenyl)-, (E)- | HCID 6448859 | 52.3% |
反応手順
Substantially the same procedure as in Example 7 was repeated using 2.5 g (12.6 mmol) of 5,6-diamino-1,3-diethyluracil and 2.9 g (13.9 mmol) of 4-methoxy-2,5-dimethylcinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 2.43 g (yield 52%) of Compound 74 as white crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05484920 |
| 出典データセット | uspto-grants-1996_01 |
| ORD ID | ord-88795606de874e8584742da57ead9c5a |
| 出典メモ | uspto-grants-1996_01 |