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3-(1,3-Benzodioxol-5-yl)prop-2-enoic acid → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(1,3-benzodioxol-5-yl)ethenyl)-1,3-diethyl-, (E)-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(1,3-Benzodioxol-5-yl)prop-2-enoic acid | HCID 16917 | — |
| 反応物 | 5,6-Diamino-1,3-diethyluracil | HCID 4572133 | — |
| 生成物 | 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(1,3-benzodioxol-5-yl)ethenyl)-1,3-diethyl-, (E)- | HCID 6448863 | 38% |
反応手順
Substantially the same procedure as in Example 7 was repeated using 2.0 g (10.1 mmol) of 5,6-diamino-1,3-diethyluracil and 2.33 g (12.1 mmol) of 3,4methylenedioxycinnamic acid. Then, the resultant crude crystals were recrystallized from dimethylformamide/water to give 1.34 g (yield 38%) of Compound 78 as a yellowish green powder.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05484920 |
| 出典データセット | uspto-grants-1996_01 |
| ORD ID | ord-95ac9307624d4b3bab7f5b9483857a51 |
| 出典メモ | uspto-grants-1996_01 |