HCID 3126210、化合物 → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(4-butoxyphenyl)ethenyl)-1,3-diethyl-, (E)-

HRID 375309ノート

反応式

HRID 375309 の反応式
[NH2:1][C:2]1[C:3](=[O:14])[N:4]([CH2:12][CH3:13])[C:5](=[O:11])[N:6]([CH2:9][CH3:10])[C:7]=1[NH2:8].[CH2:15]([O:19][C:20]1[CH:30]=[CH:29][C:23]([CH:24]=[CH:25][C:26](O)=O)=[CH:22][CH:21]=1)[CH2:16][CH2:17][CH3:18]>>[CH2:15]([O:19][C:20]1[CH:21]=[CH:22][C:23](/[CH:24]=[CH:25]/[C:26]2[NH:1][C:2]3[C:3](=[O:14])[N:4]([CH2:12][CH3:13])[C:5](=[O:11])[N:6]([CH2:9][CH3:10])[C:7]=3[N:8]=2)=[CH:29][CH:30]=1)[CH2:16][CH2:17][CH3:18]

参加物

3

反応物 2

HCID 3126210HCID 3126210、化合物HCID 45721335,6-Diamino-1,3-diethyluracil

生成物 1

HCID 64488801H-Purine-2,6-dione, 3,7-dihydro-8-(2-(4-butoxyphenyl)ethenyl)-1,3-diethyl-, (E)-収率 53%

実験手順

Substantially the same procedure as in Example 7 was repeated using 3.00 g (15.1 mmol) of 5,6-diamino-1,3-diethyluracil and 3.67 g (16.7 mmol) of 4-butoxycinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 3.04 g (yield 53%) of Compound 104 as pale yellow needles.

後処理

  1. customThen, the resultant crude crystals were recrystallized from dioxane/water

出典と根拠

ORDレコード
ord-9a496baa15254ffd98c3f87ef40ee4b6
出典データセット
uspto-grants-1996_01
特許番号
US05484920

反応ノート

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