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HRID 375311作成日:2026年10月26日

2-Propenoic acid, 3-(methoxyphenyl)- → 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(2-methoxyphenyl)ethenyl)-, (E)-

https://huagongshe.com/reaction/375311

反応式

関与物質

役割名称HCID仕込み量
反応物2-Propenoic acid, 3-(methoxyphenyl)-HCID 26862—
反応物5,6-Diamino-1,3-diethyluracilHCID 4572133—
生成物1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(2-methoxyphenyl)ethenyl)-, (E)-HCID 644888424%

反応手順

Substantially the same procedure as in Example 7 was repeated using 2.5 g (12.6 mmol) of 5,6-diamino-1,3-diethyluracil and 2.48 g (13.9 mmol) of 2-methoxycinnamic acid. Then, the resultant crude crystals were recrystallized from tetrahydrofuran/water to give 990 mg (yield 24%) of Compound 108 as yellow grains.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05484920
出典データセットuspto-grants-1996_01
ORD IDord-ee243197fd604ce6be37645a14714dbd
出典メモuspto-grants-1996_01