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HRID 375319作成日:2026年10月26日

3-(2,4-Dimethoxyphenyl)prop-2-enoic acid → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2,4-dimethoxyphenyl)ethenyl)-1,3-dipropyl-, (E)-

https://huagongshe.com/reaction/375319

反応式

関与物質

役割名称HCID仕込み量
反応物3-(2,4-Dimethoxyphenyl)prop-2-enoic acidHCID 85636—
反応物5,6-Diamino-1,3-dipropyl-2,4(1H,3H)-pyrimidinedioneHCID 5098605—
生成物1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2,4-dimethoxyphenyl)ethenyl)-1,3-dipropyl-, (E)-HCID 6448780—

反応手順

Substantially the same procedure as in Reference Example 1 was repeated using 3.0 g (13.3 mmol) of 5,6-diamino-1,3-dipropyluracil and 3.04 g (14.60 mmol) of 2,4-dimethoxycinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 1.26 g (yield of Compound 24 as white crystals.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05484920
出典データセットuspto-grants-1996_01
ORD IDord-a523df9c0e4647fd9aacc2183c8062d2
出典メモuspto-grants-1996_01