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HRID 375327作成日:2026年10月25日

3-(2-Chlorophenyl)acrylic acid → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2-chlorophenyl)ethenyl)-1,3-dipropyl-, (E)-

https://huagongshe.com/reaction/375327

反応式

関与物質

役割名称HCID仕込み量
反応物3-(2-Chlorophenyl)acrylic acidHCID 19567—
反応物5,6-Diamino-1,3-dipropyl-2,4(1H,3H)-pyrimidinedioneHCID 5098605—
生成物1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2-chlorophenyl)ethenyl)-1,3-dipropyl-, (E)-HCID 644878882%

反応手順

Substantially the same procedure as in Reference Example 1 was repeated using 3.00 g (13.3 mmol) of 5,6-diamino-1,3-dipropyluracil and 2.67 g (14.6 mmol) of 2-chlorocinnamic acid. Then, the resultant crude crystals were recrystallized from toluene to give 3.72 g (yield 82%) of Compound 40 as white needles.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05484920
出典データセットuspto-grants-1996_01
ORD IDord-8983c88acb5f4a9391fbf53c298cba1e
出典メモuspto-grants-1996_01