化工社化工社 化学情報印刷レポート · 研究参考用
3-(3-Chlorophenyl)prop-2-enoic acid → (E)-8-(3-Chlorostyryl)-1,3-diethylxanthine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(3-Chlorophenyl)prop-2-enoic acid | HCID 74631 | — |
| 反応物 | 5,6-Diamino-1,3-diethyluracil | HCID 4572133 | — |
| 生成物 | (E)-8-(3-Chlorostyryl)-1,3-diethylxanthine | HCID 6448908 | 42.1% |
反応手順
Substantially the same procedure as in Example 7 was repeated using 3.50 g (17.7 mmol) of 5,6-diamino-1,3-diethyluracil and 3.55 g (19.4 mmol) of 3-chlorocinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 2.57 g (yield 42%) of Compound 132 as white plates.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05484920 |
| 出典データセット | uspto-grants-1996_01 |
| ORD ID | ord-21e51b3c0f6c49adb83093a86af3c8e2 |
| 出典メモ | uspto-grants-1996_01 |