HCID 735855、化合物 → 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(3-phenoxyphenyl)ethenyl)-, (E)-

HRID 375376ノート

反応式

HRID 375376 の反応式
[NH2:1][C:2]1[C:3](=[O:14])[N:4]([CH2:12][CH3:13])[C:5](=[O:11])[N:6]([CH2:9][CH3:10])[C:7]=1[NH2:8].[O:15]([C:22]1[CH:23]=[C:24]([CH:30]=[CH:31][CH:32]=1)[CH:25]=[CH:26][C:27](O)=O)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH2:12]([N:4]1[C:3](=[O:14])[C:2]2[NH:1][C:27](/[CH:26]=[CH:25]/[C:24]3[CH:30]=[CH:31][CH:32]=[C:22]([O:15][C:16]4[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=4)[CH:23]=3)=[N:8][C:7]=2[N:6]([CH2:9][CH3:10])[C:5]1=[O:11])[CH3:13]

参加物

3

反応物 2

HCID 735855HCID 735855、化合物HCID 45721335,6-Diamino-1,3-diethyluracil

生成物 1

HCID 64489791H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(3-phenoxyphenyl)ethenyl)-, (E)-収率 63%

実験手順

Substantially the same procedure as in Example 7 was repeated using 3.00 g (15.1 mmol) of 5,6-diamino-1,3-diethyluracil and 4.00 g (16.7 mmol) of 3-phenoxycinnamic acid. Then, the resultant -crude crystals were recrystallized from dioxane/water to give 3.82 g (yield 63%) of Compound 182 as pale yellow needles.

後処理

  1. customThen, the resultant -crude crystals were recrystallized from dioxane/water

出典と根拠

ORDレコード
ord-a07365cef28e42f9bc2825efdeae825d
出典データセット
uspto-grants-1996_01
特許番号
US05484920

反応ノート

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