(R)-2-tert-butoxycarbonylamino-3-hydroxy propionic acid → N-[N-(tert-butoxycarbonyl)-D-seryl]-L-cysteine methyl ester

HRID 375729

反応式

HRID 375729 の反応式
Cl.[CH3:2][O:3][C:4](=[O:9])[C@H:5]([CH2:7][SH:8])[NH2:6].[C:10]([O:14][C:15]([NH:17][C@@H:18]([C:21](O)=[O:22])[CH2:19][OH:20])=[O:16])([CH3:13])([CH3:12])[CH3:11]>>[CH3:2][O:3][C:4](=[O:9])[C@H:5]([CH2:7][SH:8])[NH:6][C:19](=[O:20])[C@@H:18]([CH2:21][OH:22])[NH:17][C:15]([O:14][C:10]([CH3:11])([CH3:13])[CH3:12])=[O:16]

参加物

3

反応物 2

HCID 637603(R)-2-tert-butoxycarbonylamino-3-hydroxy propionic acidHCID 2733208L-Cysteine, methyl ester, hydrochloride

生成物 1

HCID 53744746N-[N-(tert-butoxycarbonyl)-D-seryl]-L-cysteine methyl ester

実験手順

L-Cysteine methyl ester hydrochloride was acylated with N-(tert-butoxycarbonyl)-D-serine by using in an analogous manner the procedure described in Example 1(e) to yield N-[N-(tert-butoxycarbonyl)-D-seryl]-L-cysteine methyl ester as white crystals of m.p. 105°-106° C.

出典と根拠

ORDレコード
ord-4bf35a3110a6436aaed5161a4ca30ea7
出典データセット
uspto-grants-1996_01
特許番号
US05486466

関連ノート

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