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N,N,N',N'-Tetramethylethylenediamine → HCID 178506664、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N,N,N',N'-Tetramethylethylenediamine | HCID 8037 | — |
| 反応物 | 2,2-Difluoro-1,3-benzodioxole | HCID 74103 | — |
| 反応物 | Butyllithium | HCID 178418339 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 溶媒 | Butane | HCID 7843 | — |
| 生成物 | HCID 178506664 | HCID 178506664 | — |
反応手順
39.3 g (339 mmol) of N,N,N',N'-tetramethylethylenediamine are added dropwise under a nitrogen atmosphere at from -15° to -10° C. to 137.8 g (409 mmol) of n-butyllithium solution (19.0% in toluene). The resulting reaction mixture is added dropwise at from -15° to -10° C. under a nitrogen atmosphere to a solution of 53.3 g (337 mmol) of 2,2-difluoro-1,3-benzodioxole in 46 ml of toluene, n-butane being formed in addition to the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05420301 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-3582885ae8144c71a31f109c4e589b25 |
| 出典メモ | uspto-grants-1995_05 |