化工社化工社 化学情報印刷レポート · 研究参考用
Methyl iodide → 5,10-Dimethyl-5,10-dihydrobenzo(a)phenazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl iodide | HCID 6328 | — |
| 反応物 | 1,2-Dimethoxyethane | HCID 8071 | — |
| 反応物 | Benzo(A)Phenazine | HCID 136045 | — |
| 反応物 | Potassium alloy, nonbase, K,Na | HCID 16211683 | — |
| 生成物 | 5,10-Dimethyl-5,10-dihydrobenzo(a)phenazine | HCID 22055362 | — |
反応手順
This phenazine was reduced with a 3:1 potassium/sodium metal alloy in dimethoxyethane, to the brick red alkali metal adduct. Alkylation occurred over 1 hour with addition of iodomethane. Residual K/Na alloy was quenched with addition of ethanol. The product was isolated with column chromatography and was recrystallized from ethylacetate/hexane. 2.0 grams of product was isolated for a 38% overall yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06020987 |
| 出典データセット | uspto-grants-2000_02 |
| ORD ID | ord-cf2a1a7bd08145b3b9e3448a24871c89 |
| 出典メモ | uspto-grants-2000_02 |