Fluorobenzene → HCID 53719400、化合物

HRID 377051ノート

反応式

HRID 377051 の反応式
[Cl-].[Al+3].[Cl-].[Cl-].[F:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.Cl[CH:13]([Si:15]([CH3:18])([Cl:17])[Cl:16])Cl.O=P(Cl)(Cl)Cl>[Cl-].[Al+3].[Cl-].[Cl-].CCCCCC>[F:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[CH:13]([Si:15]([CH3:18])([Cl:17])[Cl:16])[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[F:5]

参加物

7

反応物 4

HCID 10008FluorobenzeneHCID 24813Phosphorus oxychlorideHCID 73787Silane, dichloro(dichloromethyl)methyl-HCID 6451240Aluminum(III) Chloride

生成物 1

HCID 53719400HCID 53719400、化合物収率 65.5%

試薬・触媒・溶媒 2

HCID 6451240Aluminum(III) Chloride触媒HCID 8058Hexane溶媒2 回

実験手順

In a 100 ml, three-necked, frame dried, round bottom flask, aluminum chloride 1.679 (12.5 mmol), fluorobenzene 37.93 ml (404 mmol), and (dichloromethyl)methyldichlorosilane 7.08 ml (50.5 mmol) were reacted for 2 hours as in EXAMPLE 1. The aluminum chloride catalyst was quenched with POCl3 1.15 ml (12.5 mmol) and then stirred for another 1 hour to complete the deactivation. Freshly distilled hexane (50 ml) was added to the reaction mixture and insoluble solids in hexane were filtered from the organic solution. After hexane and fluorobenzene were distilled, the reaction products were vacuum distilled to give 10.49 g of [bis(fluorophenyl)methyl]methyldichlorosilane as a mixture of isomers (bp; 103° C./0.2 torr, yield; 65%).

後処理

  1. customIn a 100 ml, three-necked, frame dried
  2. filtrationwere filtered from the organic solution
  3. distillationAfter hexane and fluorobenzene were distilled
  4. distillationdistilled

出典と根拠

ORDレコード
ord-97bd4a72bb3a479f9f8058ef444b5a54
出典データセット
uspto-grants-2000_02
特許番号
US06022987

反応ノート

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