1,8-Diazabicyclo(5.4.0)undec-7-ene → 1-(3-Methoxyphenyl)-2-(ethoxycarbonylmethyl)cyclohexene

関与物質

反応手順

To a solution of ethyl [2-(3-methoxyphenyl)-cyclohexylidene]acetate (1.5 g) in benzene (20 ml) was added 1,8-diazabicyclo[5.4.0]-7-undecene (1 ml) and the mixture was stirred for 3 days under reflux. And then the mixture was washed with water, 1N-hydrochloric acid, saturated sodium bicarbonate aqueous solution, and brine. The dried solvent was evaporated to give 1-(3-methoxyphenyl)-2-(ethoxycarbonylmethyl)cyclohexene (1.4 g).

情報源と証拠